The Cutting Edge of San Francisco Biotech Real Estate


Known as the “birthplace of biotechnology,” San Francisco is home to hundreds of biotech companies occupying multi-millions of square feet of real estate, with more development on the horizon. With South San Francisco being one of the largest biotech clusters in the world, it attracts a surge of well-educated candidates for the labor market and an abundance of large biotech and pharmaceutical companies alongside venture firms in close proximity. HM Science, a specialized life science division of Hughes Marino, provides life science companies throughout the Bay Area with best-in-class, bespoke corporate real estate services specializing in the unique needs and critical specifications of the industry. Backed by over three decades of expertise in the field, our HM Science team has represented life science companies large and small with millions of square feet of state-of-the-art laboratory and biotech space.

An Outsourced Real Estate Partner With A Life Science Focus


Putting Decades of Life Science Real Estate Experience to Work

Our immersion in the San Francisco life science market over the years has helped us cultivate a community of experts within this sector. Along with our extensive experience in sectors ranging from biotechnology, GMP manufacturing, CLIA testing laboratories, medical device & diagnostics and more, allows us to provide the right solutions to help your company succeed. We specialize in serving life science companies from needs assessment, site selection and lab planning, leasing, renewing, expanding, subleasing, buying a building or building a lab space from the ground-up. Instead of defining our clients’ issues to fit our capabilities, we listen to their needs, assess the specific lab and testing requirements required, and tailor solutions to help them meet their long-term goals of finding the right space for their business.

Schedule Consultation

Details We Take Into Consideration

  • Back-up generators and power requirements
  • Lab HVAC and handling requirements
  • Tissue culture room designs and MEP/HVAC requirements
  • Clean rooms including all ISO levels and CLIA
  • Benching styles based on scientific procedures
  • Hazardous materials storage
  • House vs. tenant provided services
  • Number of control zones
  • Animal care and vivariums
  • Building engineering/support on a 24/7 basis
  • Floor load capacity
  • Vibration sensitive equipment
  • reight elevator requirements
  • Natural light in lab areas
  • Water needs
  • Gas requirements and hookups
  • Chemical limits
  • Flammable limits
  • Lab IT and data needs
  • Equipment planning
  • Lab MEP planning
  • Physical and cultural connection between lab and office

Our Life Science Locations

With offices in every major life science hub in the U.S., our team has experience assisting biotech clients in every market in the country. We offer local expertise to our clients with facilities from east to west and everywhere in between—Boston to San Diego, Raleigh-Durham to Seattle, San Francisco to Boulder, and around the world.


As a spin out of a larger company, Agena had less than 12 months to hire an executive management team and build the infrastructure to support a new company with worldwide revenues approaching $50 million. This included IT systems, finance and administrative teams, as well as a new corporate headquarters including R&D and manufacturing. Hughes Marino listened closely and helped guide an efficient and highly effective, accelerated process of selecting and negotiating a new facility in just four months. Hughes Marino’s unique in-house construction management team seamlessly took it from there, delivering an on-time, on budget tenant buildout from the ground up in just five months. We could not have asked for more, or been more happy with the results.

Terance Kinninger

CFO, Agena Bioscience, Inc.

I have worked with Hughes Marino over several decades and have successfully completed more than a few major projects from start up through expansion phases. The Hughes Marino team has always proved to be professional, detailed, dedicated and most importantly, they get the job done! Their continued follow up, post deal, has always been appreciated as well. I highly recommend them.

Peter Ellman

CEO, Certis Oncology Solutions

They go way beyond finding you a space—it’s more like a relationship with an industry specialist. The level of service and attention to detail is exceptional. It’s been a great relationship.

Christopher Calhoun

Former CEO, Cytori

I can’t say enough good things about Hughes Marino. They were referred to us by one of our investors. We were trying to cut our rent in half, and we were already in a lease that had expired. Needless to say, we had little leverage to negotiate. Hughes Marino’s detailed knowledge of the lab market and improvement costs, not to mention our landlord itself, made this deal come through. We were on a short timeline to execute and reduce our monthly costs. Hughes Marino pulled through. We were able to cut our rent in half five days after the lease was executed. I am very happy we had Hughes Marino represent us as they did an excellent job. I would be glad to recommend their services to any business that has real estate needs.

Thomas Zindrick

President & CEO, Genelux Corporation

Hughes Marino has my highest of recommendations. They provided exceptional results, knowledge and professionalism, and delivered far beyond our expectations. AnaptysBio’s facility needs will be well served for years to come.

Tom Smart

Former Chairman & CEO, AnaptysBio

From project inception to our grand opening celebration, Hughes Marino was with us every step of the way. The on-time/on-budget result was a magnificent state-of-the-art campus that now enables legendary discovery to scientists around the globe.

Bill Kullback

CFO, BioLegend

Hughes Marino helped us clarify our requirements and surveyed all of our options. Through their robust process, their team negotiated the building of our choice and preferred location to become the low-cost leader. In addition to covering most of our tenant improvement costs, they were able to negotiate the credit enhancement requirements down to a favorable level. They also negotiated a year of free occupancy so we could move into a portion of the premises now in order to meet our immediate expansion requirements. Hughes Marino provided guidance on the schedules and cost evaluations to refine our tenant improvement scope and will oversee the remodel of the new facility. We could not have pulled it all together without their collaboration and tireless support.

David Wellis

CEO, Excellos

Hughes Marino has talented real estate negotiators, strategists and advisors and they are a pleasure to work with. They understand our future laboratory goals and objectives while keeping an eye on all of the details associated with a complex relocation assignment. We remain a loyal client of Hughes Marino and highly recommend them to anyone looking for a great tenant broker firm

David Keihn

SVP & CFO, Cellnetix

Hughes Marino has represented me at multiple medical device companies where I’ve been CEO and they have been an instrumental partner in supporting our growth and understanding our requirements. They have spent the time to get to know our operational requirements and our financial goals, executing as fierce advocates on our behalf. Hughes Marino is the go-to firm in representing medical device and health care companies that have specialized requirements like ours.

John Kilcoyne

CEO, JenaValve

Hughes Marino has proven to be our trusted partner globally for all of our real estate acquisition, disposition, renewal and lease administration services. Supporting the company in over a dozen projects throughout the United States and Europe, the leadership and support we’ve received around all of our corporate real estate has been exceptional. Their team is proactive, insightful and provides tremendous coaching for our entire senior leadership team. Their advice has always been direct and creative, always with our best interests in mind.

Martin Hales

Director, Real Estate and Facilities, Vyaire Medical

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Whether you’re looking for your first lab space or expanding your national lab footprint, we specialize in serving life science companies with every facility need. From leasing, renewing, expanding, buying a building or building a lab space from the ground-up, our focus and specialization in biotech makes us trusted experts in everything life science companies need for success.

Meet Our Team of World-Class
Life Science Real Estate Experts

Widely recognized as the corporate real estate partner of choice for life science companies across the nation, we are proud to bring our three decades of specialization and best of class representation to our clients no matter where they operate and what their needs are.


Steven Gorup

Director, LEED AP BD+C

Robert Rackleff

Chief Financial Officer

Kathryn Richman, Esq.

General Counsel

Brenna Palmer

Vice President of Operations

Jaime LeMaire

Vice President of Marketing

Heather Fox

Finance Director

Briana Iverson

Marketing Director

Seth Hall

Information Technology Director

David Rubenstein

Recruiting Director

Erica Diersing

Senior Operations Manager

Andrea Kirklen

Client Relations Director

Ashley Meyer

Broker Relations Director

Kristen Hellquist

Programs Engagement Director

Stacy Bates

Corporate Operations Director

Rachel Rossi

Bay Area Operations Director

Hilary Metcalf

Senior Broker Relations Manager

Samara Sullivan

Chief of Staff

Thea Arnone

Talent Acquisition Director

Jean Silveira

Human Resources Operations Manager

Scott Iverson

Senior Client Operations Manager

Hope Fox

Senior Client Operations Manager

Ayu Nirwani

Client Relations Assistant Director

Breanna Ferraro

Senior Accounting Manager

Elizabeth Robinson

Senior Client Operations Manager

Paisley Bittner

Operations Manager

Peter Lange

Database Project Manager

Zachary Buck

Software Engineer

Kristin Beshore

Senior Programs Operations Manager

Meghan Nowell

Senior Client Operations Manager

Chiara Riley

Senior Programs Manager

Natalie Galvan

Senior Client Relations Manager

Nathan Castillo

Senior Information Technology Specialist

Lindsay Culver

Life Science Senior Operations Manager

Thananya Scott

Senior Client Relations Manager

Edson Muzada

Senior Graphic Designer

Michael Capek

Marketing Manager

Katherine Delehant

Programs Manager

Alison Dunks

Operations Coordinator

Remona Robin

Client Relations Specialist

JR Ramirez

Data Validation Coordinator

Benj Salvador

Information Technology Specialist

Kaila Kolbeck

Graphic Designer

Tamra Knutzen

Program Campaign Manager

Valencia Howard

Office Manager

Chelsea Hayes

Copywriter & Content Strategist

Amanda Chung

Marketing Coordinator

Jared Rahming

Legal and Operations Administrator

Adriana Coelho

Data Validation Manager

The Following Life Science Organizations Are
Proudly Supported by Hughes Marino:

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