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Silicon Valley Life Science Real Estate Experts

Real Estate Strategies and Results for Silicon Valley Life Science Companies

Helping You Push the Bounds of Innovation in Silicon Valley

With its close proximity to top research universities such as Stanford and the University of San Francisco, the Silicon Valley life science sector is on a fast-growth trajectory, with genomics and pharmaceuticals leading the charge. As the field continues to develop and attract a highly educated labor pool in the surrounding region, so too will the real estate landscape that supports it. HM Science, a specialized life science division of Hughes Marino, is at the forefront of this exciting area of innovation. We specialize in serving Bay Area life science companies from needs assessment and lab planning, leasing, renewing, expanding, subleasing, buying a building or building a lab space from the ground-up.

An Outsourced Real Estate Partner With A Life Science Focus

  • BIOTECHNOLOGY
  • GMP MANUFACTURING
  • CLIA TESTING LABORATORIES
  • PATHOLOGY
  • MEDICAL DEVICE & DIAGNOSTICS
  • DIAGNOSTICS & TESTING LABORATORIES
  • INDUSTRIAL BIOTECH
  • PHARMACEUTICAL
  • COMMERCIAL SCALE-UPS
  • HEALTH TECHNOLOGY

Creating Environments that Foster Scientific Breakthroughs

For any life science company in Silicon Valley looking for its next real estate opportunity, it’s critical to understand the type of space needed based on the phase of the business. Since these specialized facilities often require complex design and safety measures to meet product quality and regulatory requirements, partnering with a real estate company that has its finger on the market pulse is a non-negotiable. Backed by over three decades of combined experience in the field, our HM Science team has represented life science companies of all sizes, totaling millions of square feet, assisting start-ups to publicly funded organizations find state-of-the-art laboratory and biotech space. We pride ourselves on delivering best in class, bespoke corporate real estate services, focused on the unique needs and critical specifications of our life science clients, large and small.

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Details We Take Into Consideration

  • Back-up generators and power requirements
  • Lab HVAC and handling requirements
  • Tissue culture room designs and MEP/HVAC requirements
  • Clean rooms including all ISO levels and CLIA
  • Benching styles based on scientific procedures
  • Hazardous materials storage
  • House vs. tenant provided services
  • Number of control zones
  • Animal care and vivariums
  • Building engineering/support on a 24/7 basis
  • Floor load capacity
  • Vibration sensitive equipment
  • Freight elevator requirements
  • Natural light in lab areas
  • Water needs
  • Gas requirements and hookups
  • Chemical limits
  • Flammable limits
  • Lab IT and data needs
  • Equipment planning
  • Lab MEP planning
  • Physical and cultural connection between lab and office

Our Life Science Locations

With offices in every major life science hub in the U.S., our team has experience assisting biotech clients in every market in the country. We offer local expertise to our clients with facilities from east to west and everywhere in between—Boston to San Diego, Raleigh-Durham to Seattle, San Francisco to Boulder, and around the world.

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Testimonials

  • I can’t say enough good things about Hughes Marino. They were referred to us by one of our investors. We were trying to cut our rent in half, and we were already in a lease that had expired. Needless to say, we had little leverage to negotiate. Hughes Marino’s detailed knowledge of the lab market and improvement costs, not to mention our landlord itself, made this deal come through. We were on a short timeline to execute and reduce our monthly costs. Hughes Marino pulled through. We were able to cut our rent in half five days after the lease was executed. I am very happy we had Hughes Marino represent us as they did an excellent job. I would be glad to recommend their services to any business that has real estate needs.

    Thomas Zindrick

    President & CEO, Genelux Corporation

  • From project inception to our grand opening celebration, Hughes Marino was with us every step of the way. The on-time/on-budget result was a magnificent state-of-the-art campus that now enables legendary discovery to scientists around the globe.

    Bill Kullback

    CFO, BioLegend

  • Hughes Marino helped us clarify our requirements and surveyed all of our options. Through their robust process, their team negotiated the building of our choice and preferred location to become the low-cost leader. In addition to covering most of our tenant improvement costs, they were able to negotiate the credit enhancement requirements down to a favorable level. They also negotiated a year of free occupancy so we could move into a portion of the premises now in order to meet our immediate expansion requirements. Hughes Marino provided guidance on the schedules and cost evaluations to refine our tenant improvement scope and will oversee the remodel of the new facility. We could not have pulled it all together without their collaboration and tireless support.

    David Wellis

    CEO, Excellos

  • Hughes Marino has represented me at multiple medical device companies where I’ve been CEO and they have been an instrumental partner in supporting our growth and understanding our requirements. They have spent the time to get to know our operational requirements and our financial goals, executing as fierce advocates on our behalf. Hughes Marino is the go-to firm in representing medical device and health care companies that have specialized requirements like ours.

    John Kilcoyne

    CEO, JenaValve

  • Hughes Marino has my highest of recommendations. They provided exceptional results, knowledge and professionalism, and delivered far beyond our expectations. AnaptysBio’s facility needs will be well served for years to come.

    Tom Smart

    Chairman and CEO, AnaptysBio

  • As a spin out of a larger company, Agena had less than 12 months to hire an executive management team and build the infrastructure to support a new company with worldwide revenues approaching $50 million. This included IT systems, finance and administrative teams, as well as a new corporate headquarters including R&D and manufacturing. Hughes Marino listened closely and helped guide an efficient and highly effective, accelerated process of selecting and negotiating a new facility in just four months. Hughes Marino’s unique in-house construction management team seamlessly took it from there, delivering an on-time, on-budget tenant buildout from the ground up in just five months. We could not have asked for more, or been more happy with the results.

    Terance Kinninger

    CFO, Agena Bioscience, Inc.

  • I have worked with Hughes Marino over several decades and have successfully completed more than a few major projects from start up through expansion phases. The Hughes Marino team has always proved to be professional, detailed, dedicated and most importantly, they get the job done! Their continued follow up, post deal, has always been appreciated as well. I highly recommend them.

    Peter Ellman

    CEO, Certis Oncology Solutions

Whether you’re looking for your first lab space or expanding your national lab footprint, we specialize in serving life science companies with every facility need. From leasing, renewing, expanding, buying a building or building a lab space from the ground-up, our focus and specialization in biotech makes us trusted experts in everything life science companies need for success.

Frequently Asked Questions

How is real estate for lab and biotech companies different from standard commercial space?

Lab, testing, production, fulfillment and R&D facilities require specialized infrastructure, engineering and regulatory considerations that go far beyond traditional office or industrial environments.

When should a growing life science company in Silicon Valley start planning for new space?

Most organizations in Silicon Valley benefit from starting 12 to 18 months ahead of a potential move or renewal so they can evaluate all scientific, operational and financial variables.

What support does Hughes Marino provide during lab planning and build-outs?

Our team partners closely with architects, engineers, planners and project managers to ensure scientific workflows, technical requirements and long-term needs are fully supported.

What types of life science companies do you work with in Silicon Valley?

We work with a broad range of organizations in Silicon Valley including biotechnology, pharmaceutical, medical device, diagnostics, GMP manufacturing and clinical laboratories, helping companies at all stages—from startups to global enterprises.

Do you help with both leasing and purchasing properties in Silicon Valley?

Yes. Our team provides full tenant and buyer representation, whether you’re expanding, relocating or purchasing space for labs, offices or full campuses.

Can you assist with lab design and construction?

Absolutely. We offer in-house architects, lab planners and construction project managers to ensure your space meets scientific, operational and regulatory requirements.

How do you find the right location for a life science company in Silicon Valley?

We consider factors like proximity to talent, supply chain logistics, research hubs and long-term growth plans to secure locations that align with your business strategy.

Do you provide support for complex lease or purchase negotiations?

Yes. Our team has extensive experience negotiating agreements in Silicon Valley of all sizes and complexities, helping ensure favorable terms and predictable costs for our clients.

Can you support companies nationally or internationally?

Yes. While we are U.S.-based, we provide strategy, insight and representation for life science companies across the country and around the globe.

Meet Our Team of World-Class
Life Science Real Estate Experts

Widely recognized as the corporate real estate partner of choice for life science companies across the nation, we are proud to bring our three decades of specialization and best of class representation to our clients no matter where they operate and what their needs are.

The Following Life Science Organizations Are Proudly Supported by Hughes Marino: